个人简介

吕瀛，研究员，bat365正版唯一官网博士生导师。2019年于中国科学院生物物理研究所获得博士学位，2020-2026年在美国MD安德森癌症中心开展博士后研究。获得国家自然科学基金优秀青年科学基金（海外）项目资助。 院校引进人才，2026年2月加入院校。

主要研究内容

从事皮肤稳态维持与再生修复方向的研究，结合小鼠模型、类器官培养及高通量多组学分析，系统解析在发育、衰老和疾病过程中皮肤干细胞的调控机制，重点关注基因组“暗物质”转座子在其中发挥的功能，并在此基础上探索相关疾病的治疗靶点与干预策略。前期成果以第一作者发表于Cell、Genes & Development等期刊。

代表性成果

Ying Lyu#, Soo Jin Kim, Ericka S Humphrey, Richa Nayak, Yinglu Guan, Qingnan Liang, Kun Hee Kim, Yukun Tan, Jinzhuang Dou, Huandong Sun, Xingzhi Song, Priyadharsini Nagarajan, Kamryn N Gerner-Mauro, Kevin Jin, Virginia Liu, Rehman H Hassan, Miranda L Johnson, Lisa P Deliu, Yun You, Anurag Sharma, H Amalia Pasolli, Yue Lu, Jianhua Zhang, Vakul Mohanty, Ken Chen, Youn Joo Yang, Taiping Chen, Yejing Ge*. Stem cell activity-coupled suppression of endogenous retrovirus governs adult tissue regeneration. Cell , 2024, 187(26), 7414-7432. (IF="42.5)

2. Ying Lyu#, Yinglu Guan#, Lisa Deliu, Ericka Humphrey, Joanna K Frontera, Youn Joo Yang, Daniel Zamler, Kun Hee Kim, Vakul Mohanty, Kevin Jin, Virginia Liu, Jinzhuang Dou, Lucas J Veillon, Shwetha V Kumar, Philip L Lorenzi, Yang Chen, Kathleen M McAndrews, Sergei Grivennikov, Xingzhi Song, Jianhua Zhang, Yuanxin Xi, Jing Wang, Ken Chen, Priyadharsini Nagarajan, Yejing Ge*. KLF5 governs sphingolipid metabolism and barrier function of the skin. Genes & Development , 2022, 36(13-14), 822-842. (IF="10.5)

3. Ying Lv#, Sheng Shen#, Lingjiao Xiang, Xing Jia, Yanjie Hou, Dacheng Wang, Hongyu Deng*. Functional identification and characterization of the nuclear egress complex of a gammaherpesvirus. Journal of Virology , 2019, 93(24), 10-1128. (IF="4.501)